Personal Statement: I continue to be enthused by our congenial hybrid of a formal academic medical center and a functional community hospital here in Portland. I strive to provide optimal patient care, teaching and community service.Areas of Academic Focus:Antimicrobial pharmacodynamicsHIVNational/Regional Responsibilities:Regional Chairman, Pharmacy & Therapeutics Committee, Providence HeaLth & ServicesMember, PPMC Clinical Decision Support CommitteeNorthwest AIDS Education and Training Center preceptorPast president, Infectious Diseases Society of OregonAd hoc member, Anti-Infective Drugs Advisory Committee, Food and Drug Administration (FDA)Member, Editorial Board, Antimicrobial Agents ChemotherapyChairperson, PPMC Clinical Decision Support CommitteeSignificant Publications:Gilbert, Leggett: Chapter on Aminoglycosides. Mandell, Doyles and Bennett. Principles and Practice of Infectious Diseases. Elsevier; Philadelphia, 2009-10Leggett J. Approach to Fever and Suspected Infection in the Normal Host. Chapter 302. Cecil's Medicine, 23rd Edition, Saunders, 2008; pp 2112-2118.Saravolatz LD, Leggett J. Gatifloxacin, gemifloxacin, and moxifloxacin: the role for three new fluoroquinolones. Clin Infect Dis 2003; 37:1210-1215.Gilbert DN et al. A randomized comparison of the safety and efficacy of once-daily gentamicin or thrice-daily gentamicin in combination with ticarcillin-clavulanate. Am J Med 1998;105:182-91.Bermada S et al. Correlation of tobramycin-induced inhibition of protein synthesis with postantibiotic effect in E. coli. Antimicrob Agents Chemother 1993;37:2678-2683.Leggett JE et al. Comparative antibiotic dose-effect relationships at several dosing intervals in murine pneumonitis and thigh infection models. J Infect Dis 1989;159:281-92.Vogelman B et al. Correlation of antimicrobial pharmacokinetic parameters with therapeutic efficacy in an animal model. J Infect Dis 1988;158:831-47.Vogelman B et al. The in vivo postantibiotic effect in a thigh infection in neutropenic mice. J Infect Dis 1988;157:287-98.Presentations:MRSA: An Evolving PathogenBad Bugs, No Drugs: Big PhRMA and the FDA.Limitations of animal models.Pharmacokinetics/pharmacodynamics.Teaching Responsibilities:Attending for the Infectious Diseases Service 12 months a year.Preceptor for internal medicine residents in weekly HIV clinics.
Medical degree: University of Kentucky, Lexington
Residency: University of Wisconsin, Madison - Internal Medicine
Fellowship: University of Wisconsin, Madison - Infectious Diseases