Gastrointestinal Cancer Research

Todd S. Crocenzi, M.D., is exploring ways in which immunotherapy can be integrated effectively into standard treatments for colorectal cancer and other cancers of the gastrointestinal system. 

Genitourinary Cancer Research

Brendan D. Curti, M.D., focuses on developing immunotherapies to treat malignancies of the prostate, kidney and bladder.

Laboratory of Molecular and Tumor Immunology

The Laboratory of Molecular and Tumor Immunology, led by Bernard A. Fox, Ph.D., hypothesizes that a primary reason for the failure of past tumor vaccine strategies is that the magnitude of the antitumor immune response is insufficient to mediate tumor regression. One answer to this is to create a lymphopenic host, reconstitute that host with lymphocytes and then inoculate with a tumor vaccine.

Integrated Therapies Laboratory

The Integrated Therapies Laboratory is a collaborative research effort between Michael J. Gough, Ph.D., and Marka R. Crittenden, M.D., Ph.D. It encompasses their overlapping research interest into the ability of cytotoxic therapy to provide large-scale cancer cell death in vivo, while modifying the profile of immune cells within the tumor.