Research

The Earle A. Chiles Research Institute

The Earle A. Chiles Research Institute (EACRI) is a multidisciplinary center devoted to health care study. Since 1960, research activities at the Providence Portland Medical Center-based EACRI have resulted in life-saving and cost-saving treatment for patients with heart disease, cancer, diabetes and infectious diseases.

Genitourinary Cancer Research

Brendan D. Curti, M.D., focuses on developing biotherapies to treat malignancies of the prostate, kidney and bladder.

Laboratory of Molecular and Tumor Immunology

The Laboratory of Molecular and Tumor Immunology, led by Bernard A. Fox, Ph.D., hypothesizes that a primary reason for the failure of past tumor vaccine strategies is that the magnitude of the antitumor immune response is insufficient to mediate tumor regression. One answer to this is to create a lymphopenic host, reconstitute that host with lymphocytes and then inoculate with a tumor vaccine.

Integrated Therapies Laboratory

The Integrated Therapies Laboratory is a collaborative research effort between Michael J. Gough, Ph.D., and Marka R. Crittenden, M.D., Ph.D. It encompasses their overlapping research interest into the ability of cytotoxic therapy to provide large-scale cancer cell death in vivo, while modifying the profile of immune cells within the tumor.